Involvement of endoplasmic reticulum stress in angiotensin II-induced NLRP3 inflammasome activation in human renal proximal tubular cells in vitro

AIM: NLRP3 inflammasome plays an important role in renal injury and may be a therapeutic target in the treatment of patients with progressive chronic kidney disease. In this study we investigated whether angiotensin II (Ang II)-induced NLRP3 inflammasome activation was linked to endoplasmic reticulu...

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Vydáno v:Acta Pharmacol Sin
Hlavní autoři: Wang, Jing, Wen, Yi, Lv, Lin-li, Liu, Hong, Tang, Ri-ning, Ma, Kun-ling, Liu, Bi-cheng
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4813084/
https://ncbi.nlm.nih.gov/pubmed/26005910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2015.21
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