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Curcumin attenuates cardiac fibrosis in spontaneously hypertensive rats through PPAR-γ activation
AIM: To investigate the effects of curcumin (Cur) on cardiac fibrosis in spontaneously hypertensive rats (SHRs) and the mechanisms underlying the anti-fibrotic effect of Cur in rat cardiac fibroblasts (CFs) in vitro. METHODS: SHRs were orally treated with Cur (100 mg·kg(−1)·d(−1)) or Cur (100 mg·kg(...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186983/ https://ncbi.nlm.nih.gov/pubmed/25132338 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.63 |
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