Piperine Attenuates Pathological Cardiac Fibrosis Via PPAR-γ/AKT Pathways

Mitogen-activated protein kinases (MAPKs) and AMP­activated protein kinase α (AMPKα) play critical roles in the process of cardiac hypertrophy. Previous studies have demonstrated that piperine activates AMPKα and reduces the phosphorylation of extracellular signal-regulated kinase (ERK). However, th...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Ma, Zhen-Guo, Yuan, Yu-Pei, Zhang, Xin, Xu, Si-Chi, Wang, Sha-Sha, Tang, Qi-Zhu
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5405163/
https://ncbi.nlm.nih.gov/pubmed/28330809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2017.03.021
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