Piperine Alleviates Doxorubicin-Induced Cardiotoxicity via Activating PPAR-γ in Mice

BACKGROUND: Oxidative stress, inflammation and cardiac apoptosis were closely involved in doxorubicin (DOX)-induced cardiac injury. Piperine has been reported to suppress inflammatory response and pyroptosis in macrophages. However, whether piperine could protect the mice against DOX-related cardiac...

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Publicat a:PPAR Res
Autors principals: Yan, Jie, Xu, Si-Chi, Kong, Chun-Yan, Zhou, Xiao-Yang, Bian, Zhou-Yan, Yan, Ling, Tang, Qi-Zhu
Format: Artigo
Idioma:Inglês
Publicat: Hindawi 2019
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6942876/
https://ncbi.nlm.nih.gov/pubmed/31933619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/2601408
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