Curcumin attenuates cardiac fibrosis in spontaneously hypertensive rats through PPAR-γ activation

AIM: To investigate the effects of curcumin (Cur) on cardiac fibrosis in spontaneously hypertensive rats (SHRs) and the mechanisms underlying the anti-fibrotic effect of Cur in rat cardiac fibroblasts (CFs) in vitro. METHODS: SHRs were orally treated with Cur (100 mg·kg(−1)·d(−1)) or Cur (100 mg·kg(...

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Bibliographic Details
Main Authors: Meng, Zhe, Yu, Xin-hui, Chen, Jun, Li, Ling, Li, Sheng
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2014
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Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186983/
https://ncbi.nlm.nih.gov/pubmed/25132338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/aps.2014.63
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