Pioglitazone Attenuates Vascular Fibrosis in Spontaneously Hypertensive Rats

Objective. We sought to investigate whether the peroxisome proliferator-activated receptor-γ (PPAR-γ) ligand pioglitazone can attenuate vascular fibrosis in spontaneously hypertensive rats (SHRs) and explore the possible molecular mechanisms. Methods. SHRs (8-week-old males) were randomly divided in...

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Autores principales: Gao, Dengfeng, Ning, Ning, Hao, Guanghua, Niu, Xiaolin
Formato: Artigo
Lenguaje:Inglês
Publicado: Hindawi Publishing Corporation 2012
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324923/
https://ncbi.nlm.nih.gov/pubmed/22550475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/856426
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