The Interrelationship between Promoter Strength, Gene Expression, and Growth Rate

In exponentially growing bacteria, expression of heterologous protein impedes cellular growth rates. Quantitative understanding of the relationship between expression and growth rate will advance our ability to forward engineer bacteria, important for metabolic engineering and synthetic biology appl...

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Autors principals: Bienick, Matthew S., Young, Katherine W., Klesmith, Justin R., Detwiler, Emily E., Tomek, Kyle J., Whitehead, Timothy A.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186888/
https://ncbi.nlm.nih.gov/pubmed/25286161
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0109105
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