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Tailoring mTOR-based therapy: molecular evidence and clinical challenges
The mTOR signaling pathway integrates inputs from a variety of upstream stimuli to regulate diverse cellular processes including proliferation, growth, survival, motility, autophagy, protein synthesis and metabolism. The mTOR pathway is dysregulated in a number of human pathologies including cancer,...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186793/ https://ncbi.nlm.nih.gov/pubmed/24024901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs.13.143 |
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