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Targeting mTOR in Glioblastoma: Rationale and Preclinical/Clinical Evidence

The mechanistic target of rapamycin (mTOR) drives several physiologic and pathologic cellular processes and is frequently deregulated in different types of tumors, including glioblastoma (GBM). Despite recent advancements in understanding the molecular mechanisms involved in GBM biology, the surviva...

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Uloženo v:
Podrobná bibliografie
Vydáno v:Dis Markers
Hlavní autoři: Mecca, Carmen, Giambanco, Ileana, Donato, Rosario, Arcuri, Cataldo
Médium: Artigo
Jazyk:Inglês
Vydáno: Hindawi 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312595/
https://ncbi.nlm.nih.gov/pubmed/30662577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9230479
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