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Targeting mTOR in Glioblastoma: Rationale and Preclinical/Clinical Evidence

The mechanistic target of rapamycin (mTOR) drives several physiologic and pathologic cellular processes and is frequently deregulated in different types of tumors, including glioblastoma (GBM). Despite recent advancements in understanding the molecular mechanisms involved in GBM biology, the surviva...

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Detalhes bibliográficos
Publicado no:Dis Markers
Main Authors: Mecca, Carmen, Giambanco, Ileana, Donato, Rosario, Arcuri, Cataldo
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312595/
https://ncbi.nlm.nih.gov/pubmed/30662577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9230479
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