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Targeting mTOR in Glioblastoma: Rationale and Preclinical/Clinical Evidence

The mechanistic target of rapamycin (mTOR) drives several physiologic and pathologic cellular processes and is frequently deregulated in different types of tumors, including glioblastoma (GBM). Despite recent advancements in understanding the molecular mechanisms involved in GBM biology, the surviva...

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Bibliografische gegevens
Gepubliceerd in:Dis Markers
Hoofdauteurs: Mecca, Carmen, Giambanco, Ileana, Donato, Rosario, Arcuri, Cataldo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi 2018
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312595/
https://ncbi.nlm.nih.gov/pubmed/30662577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9230479
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