PP242 Counteracts Glioblastoma Cell Proliferation, Migration, Invasiveness and Stemness Properties by Inhibiting mTORC2/AKT

Glioblastoma multiforme (GBM) is the most malignant brain tumor and is associated with poor prognosis due to its thorny localization, lack of efficacious therapies and complex biology. Among the numerous pathways driving GBM biology studied so far, PTEN/phosphatidylinositol-4,5-bisphosphate 3-kinase...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Cell Neurosci
Prif Awduron: Mecca, Carmen, Giambanco, Ileana, Bruscoli, Stefano, Bereshchenko, Oxana, Fioretti, Bernard, Riccardi, Carlo, Donato, Rosario, Arcuri, Cataldo
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2018
Pynciau:
Neuroscience
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5902688/
https://ncbi.nlm.nih.gov/pubmed/29692710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fncel.2018.00099
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