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Targeting mTOR in Glioblastoma: Rationale and Preclinical/Clinical Evidence

The mechanistic target of rapamycin (mTOR) drives several physiologic and pathologic cellular processes and is frequently deregulated in different types of tumors, including glioblastoma (GBM). Despite recent advancements in understanding the molecular mechanisms involved in GBM biology, the surviva...

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Bibliografiske detaljer
Udgivet i:Dis Markers
Main Authors: Mecca, Carmen, Giambanco, Ileana, Donato, Rosario, Arcuri, Cataldo
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6312595/
https://ncbi.nlm.nih.gov/pubmed/30662577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/9230479
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