Insulin-like growth factor-1 receptor (IGF-1R) as a biomarker for resistance to the tyrosine kinase inhibitor gefitinib in non-small cell lung cancer

BACKGROUND: The insulin-like growth factor-1 receptor (IGF-1R) pathway is known to play a role in the acquisition of resistance to epidermal growth factor receptor (EGFR)-specific tyrosine kinase inhibitors (TKIs) in non-small cell lung cancer (NSCLC). However, its exact role in TKI resistance has s...

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Bibliografski detalji
Glavni autori: Peled, Nir, Wynes, Murry W., Ikeda, Norihiko, Ohira, Tatsuo, Yoshida, Koichi, Qian, Jin, Ilouze, Maya, Brenner, Ronen, Kato, Yasufumi, Mascaux, Celine, Hirsch, Fred R.
Format: Artigo
Jezik:Inglês
Izdano: 2013
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186686/
https://ncbi.nlm.nih.gov/pubmed/23619944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13402-013-0133-9
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