Fluorescence In Situ Hybridization, Immunohistochemistry, and Next-Generation Sequencing for Detection of EML4-ALK Rearrangement in Lung Cancer

BACKGROUND. The U.S. Food and Drug Administration-approved method for detecting EML4-ALK rearrangement is fluorescence in situ hybridization (FISH); however, data supporting the use of immunohistochemistry (IHC) for that purpose are accumulating. Previous studies that compared FISH and IHC considere...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Pekar-Zlotin, Marina, Hirsch, Fred R., Soussan-Gutman, Lior, Ilouze, Maya, Dvir, Addie, Boyle, Theresa, Wynes, Murry, Miller, Vincent A., Lipson, Doron, Palmer, Gary A., Ali, Siraj M., Dekel, Shlomi, Brenner, Ronen, Bunn, Paul A., Peled, Nir
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2015
Assuntos:
Lung Cancer
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350802/
https://ncbi.nlm.nih.gov/pubmed/25721120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2014-0389
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