EGFR Protein Expression in Non-Small Cell Lung Cancer Predicts Response to an EGFR Tyrosine Kinase Inhibitor – A Novel Antibody for Immunohistochemistry or AQUA Technology

INTRODUCTION: Epidermal growth factor receptor (EGFR) protein expression in non-small cell lung cancer (NSCLC) is not recommended for predicting response to EGFR tyrosine kinase inhibitors (TKIs) due to conflicting results, all using antibodies detecting EGFR external domain (ED). We tested the pred...

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Autori principali: Mascaux, Celine, Wynes, Murry W., Kato, Yasufumi, Tran, Cindy, Asuncion, Bernadette Reyna, Zhao, Jason M., Gustavson, Mark, Ranger-Moore, Jim, Gaire, Fabien, Matsubayashi, Jun, Nagao, Toshitaka, Yoshida, Koichi, Ohira, Tatuso, Ikeda, Norihiko, Hirsch., Fred R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3266947/
https://ncbi.nlm.nih.gov/pubmed/21994417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-11-0209
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