Novel EGFR mutation specific antibodies for NSCLC: Immunohistochemistry as a possible screening method for EGFR mutations

BACKGROUND: Epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) predict better outcome to EGFR tyrosine kinase inhibitors (TKIs). The most common mutations are exon 19 deletions (most frequently E746-A750) and L858R point mutation in exon 21. Here, we evaluated th...

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Detalhes bibliográficos
Main Authors: Kato, Yasufumi, Peled, Nir, Wynes, Murry W., Yoshida, Koichi, Pardo, Marta, Mascaux, Celine, Ohira, Tatsuo, Tsuboi, Masahiro, Matsubayashi, Jun, Nagao, Toshitaka, Ikeda, Norihiko, Hirsch, Fred R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946481/
https://ncbi.nlm.nih.gov/pubmed/20697298
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e3181e9da60
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