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A CpG island methylator phenotype of colorectal cancer that is contiguous with conventional adenomas, but not serrated polyps
A subset of colorectal cancers (CRCs) harbor the CpG island methylator phenotype (CIMP), with concurrent multiple promoter hypermethylation of tumor-related genes. A serrated pathway in which CIMP is developed from serrated polyps is proposed. The present study characterized CIMP and morphologically...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
D.A. Spandidos
2014
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186580/ https://ncbi.nlm.nih.gov/pubmed/25289081 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2430 |
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