A CpG island methylator phenotype of colorectal cancer that is contiguous with conventional adenomas, but not serrated polyps

A subset of colorectal cancers (CRCs) harbor the CpG island methylator phenotype (CIMP), with concurrent multiple promoter hypermethylation of tumor-related genes. A serrated pathway in which CIMP is developed from serrated polyps is proposed. The present study characterized CIMP and morphologically...

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Autori principali: HOKAZONO, KOJI, UEKI, TAKASHI, NAGAYOSHI, KINUKO, NISHIOKA, YASUNOBU, HATAE, TATSUNOBU, KOGA, YUTAKA, HIRAHASHI, MINAKO, ODA, YOSHINAO, TANAKA, MASAO
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2014
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Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186580/
https://ncbi.nlm.nih.gov/pubmed/25289081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2014.2430
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