CpG Island Methylation in Sessile Serrated Adenoma/Polyp of the Colorectum: Implications for Differential Diagnosis of Molecularly High-Risk Lesions among Non-dysplastic Sessile Serrated Adenomas/Polyps

BACKGROUND: Although colorectal sessile serrated adenomas/polyps (SSA/Ps) with morphologic dysplasia are regarded as definite high-risk premalignant lesions, no reliable grading or risk-stratifying system exists for non-dysplastic SSA/Ps. The accumulation of CpG island methylation is a molecular hal...

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Veröffentlicht in:J Pathol Transl Med
Hauptverfasser: Lee, Ji Ae, Park, Hye Eun, Yoo, Seung-Yeon, Jeong, Seorin, Cho, Nam-Yun, Kang, Gyeong Hoon, Kim, Jung Ho
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Korean Society of Pathologists and the Korean Society for Cytopathology 2019
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6639709/
https://ncbi.nlm.nih.gov/pubmed/30887794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4132/jptm.2019.03.12
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