Nigramide J is a novel potent inverse agonist of the human constitutive androstane receptor

The constitutive androstane receptor (CAR, NR1I3) is very important for drug development and for understanding pharmacokinetic drug–drug interactions. We screened by mammalian one hybrid assay among natural compounds to discover novel ligands of human constitutive androstane receptor (hCAR). hCAR tr...

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Hlavní autoři: Kanno, Yuichiro, Tanuma, Nobuaki, Yatsu, Tomofumi, Li, Wei, Koike, Kazuo, Inouye, Yoshio
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Publishing Ltd 2014
Témata:
Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4186399/
https://ncbi.nlm.nih.gov/pubmed/25505573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.18
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