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Nigramide J is a novel potent inverse agonist of the human constitutive androstane receptor
The constitutive androstane receptor (CAR, NR1I3) is very important for drug development and for understanding pharmacokinetic drug–drug interactions. We screened by mammalian one hybrid assay among natural compounds to discover novel ligands of human constitutive androstane receptor (hCAR). hCAR tr...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4186399/ https://ncbi.nlm.nih.gov/pubmed/25505573 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prp2.18 |
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