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O8.02 MONITORING OF TREATMENT RESPONSE IN IDH-MUTANT GLIOMAS WITH IN-VIVO 3D MAGNETIC RESONANCE SPECTROSCOPY

The hallmark metabolic alteration in mutant IDH gliomas is the production of R-2-hydroxyglutarate (2HG). 2HG can be measured in-vivo by magnetic resonance spectroscopy of patients, representing an ideal biomarker for IDH mutant gliomas. 3D mapping of 2HG and other metabolites is important to capture...

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Main Authors: Cahill, D.P., Loebel, F., Bogner, W., Marjanska, M., Gerstner, E., Batchelor, T., Rosen, B.R., Chi, A., Andronesi, O.C.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2014
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185832/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.63
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