Volumetric relationship between 2-hydroxyglutarate and FLAIR hyperintensity has potential implications for radiotherapy planning of mutant IDH glioma patients

BACKGROUND: Gliomas with mutant isocitrate dehydrogenase (IDH) produce high levels of 2-hydroxyglutarate (2HG) that can be quantitatively measured by 3D magnetic resonance spectroscopic imaging (MRSI). Current glioma MRI primarily relies upon fluid-attenuated inversion recovery (FLAIR) hyperintensit...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Jafari-Khouzani, Kourosh, Loebel, Franziska, Bogner, Wolfgang, Rapalino, Otto, Gonzalez, Gilberto R., Gerstner, Elizabeth, Chi, Andrew S., Batchelor, Tracy T., Rosen, Bruce R., Unkelbach, Jan, Shih, Helen A., Cahill, Daniel P., Andronesi, Ovidiu C.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Basic and Translational Investigation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5063518/
https://ncbi.nlm.nih.gov/pubmed/27382115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/now100
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