Φορτώνει......
O4.08 AGI5198, AN INHIBITOR OF IDH1R132H, PROTECTS IDH1R132H HCT116 CELLS AGAINST IRRADIATION
BACKGROUND: IDH1(R132H) mutations are both inaugural events in the formation of glioma and associated with prolonged glioma patient survival. The IDH1(R132H) mutation confers a neo-enzymatic function that results in accumulation of the oncometabolite D-2-hydroxyglutarate (D-2HG), which promotes glio...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Oxford University Press
2014
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4185649/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou174.29 |
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