Low expression of Abelson interactor-1 is linked to acquired drug resistance in Bcr-Abl induced leukemia

The basis for persistence of leukemic stem cells in the bone marrow microenvironment (BMME) remains poorly understood. We present evidence that signaling crosstalk between α4 integrin and Abelson interactor-1 (Abi-1) is involved in acquisition of an anchorage-dependent phenotype and drug resistance...

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Detaylı Bibliyografya
Asıl Yazarlar: Chorzalska, Anna, Salloum, Ibrahem, Shafqat, Hammad, Khan, Saad, Marjon, Philip, Treaba, Diana, Schorl, Christoph, Morgan, John, Bryke, Christine R., Falanga, Vincent, Zhao, Thing C., Reagan, John, Winer, Eric, Olszewski, Adam, Al-Homsi, Samer, Kouttab, Nicola, Dubielecka, Patrycja M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185277/
https://ncbi.nlm.nih.gov/pubmed/24699303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/leu.2014.120
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