Expression of Abelson Interactor 1 (Abi1) Correlates with Inflammation, KRAS Mutation and Adenomatous Change during Colonic Carcinogenesis

BACKGROUND: Abelson interactor 1 (Abi1) is an important regulator of actin dynamics during cytoskeletal reorganization. In this study, our aim was to investigate the expression of Abi1 in colonic mucosa with and without inflammation, colonic polyps, colorectal carcinomas (CRC) and metastases as well...

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Autors principals: Steinestel, Konrad, Brüderlein, Silke, Steinestel, Julie, Märkl, Bruno, Schwerer, Michael J., Arndt, Annette, Kraft, Klaus, Pröpper, Christian, Möller, Peter
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393686/
https://ncbi.nlm.nih.gov/pubmed/22808230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040671
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