Expression of Abelson Interactor 1 (Abi1) Correlates with Inflammation, KRAS Mutation and Adenomatous Change during Colonic Carcinogenesis

BACKGROUND: Abelson interactor 1 (Abi1) is an important regulator of actin dynamics during cytoskeletal reorganization. In this study, our aim was to investigate the expression of Abi1 in colonic mucosa with and without inflammation, colonic polyps, colorectal carcinomas (CRC) and metastases as well...

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Detalhes bibliográficos
Main Authors: Steinestel, Konrad, Brüderlein, Silke, Steinestel, Julie, Märkl, Bruno, Schwerer, Michael J., Arndt, Annette, Kraft, Klaus, Pröpper, Christian, Möller, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393686/
https://ncbi.nlm.nih.gov/pubmed/22808230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040671
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