Expression of Abelson Interactor 1 (Abi1) Correlates with Inflammation, KRAS Mutation and Adenomatous Change during Colonic Carcinogenesis

BACKGROUND: Abelson interactor 1 (Abi1) is an important regulator of actin dynamics during cytoskeletal reorganization. In this study, our aim was to investigate the expression of Abi1 in colonic mucosa with and without inflammation, colonic polyps, colorectal carcinomas (CRC) and metastases as well...

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Main Authors: Steinestel, Konrad, Brüderlein, Silke, Steinestel, Julie, Märkl, Bruno, Schwerer, Michael J., Arndt, Annette, Kraft, Klaus, Pröpper, Christian, Möller, Peter
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393686/
https://ncbi.nlm.nih.gov/pubmed/22808230
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0040671
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