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Development of a Novel Orthotopic Non-small Cell Lung Cancer Model and Therapeutic Benefit of 2′-(2-bromohexadecanoyl)-Docetaxel Conjugate Nanoparticles

The aims of these studies were to establish an orthotopic non-small-cell lung cancer (NSCLC) mouse model, and to investigate the therapeutic efficacy of lipid-based nanoparticles (NPs) containing 2′-(2-bromohexadecanoyl)-docetaxel (Br-C16-DX) in this new model. A novel orthotopic NSCLC model was est...

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Main Authors: Peng, Lei, Feng, Lan, Yuan, Hong, Benhabbour, Soumya R., Mumper, Russell J.
格式: Artigo
語言:Inglês
出版: 2014
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185254/
https://ncbi.nlm.nih.gov/pubmed/24709328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2014.03.016
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