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Differential Cell Responses to Nanoparticle Docetaxel and Small Molecule Docetaxel at a Sub-Therapeutic Dose Range

Current preclinical evaluations of nanoparticle taxanes have focused on the effect of nanoparticle size and shape on the efficacy and toxicity. It is generally assumed that nanoparticle therapeutics have the same cellular response on tumor and normal cells as their small molecule counterparts. Here,...

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Detalhes bibliográficos
Main Authors: Wang, Edina C., Sinnott, Rebecca, Werner, Michael E., Sethi, Manish, Whitehurst, Angelique W., Wang, Andrew Z.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3912219/
https://ncbi.nlm.nih.gov/pubmed/23916886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nano.2013.07.012
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