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Oil-filled Lipid Nanoparticles Containing 2’-(2-bromohexadecanoyl)-docetaxel for the Treatment of Breast Cancer

A docetaxel (DX) lipid conjugate 2’-(2-bromohexadecanoyl)-docetaxel (2-Br-C16-DX) is synthesized to enhance the drug loading, entrapment and retention in liquid oil-filled lipid nanoparticles (NPs). The conjugate is successfully entrapped in the previously optimized NPs with an entrapment efficiency...

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Autores principales: Feng, Lan, Benhabbour, Soumya R., Mumper, Russell J.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3858483/
https://ncbi.nlm.nih.gov/pubmed/23606545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201300017
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