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Oil-filled Lipid Nanoparticles Containing 2’-(2-bromohexadecanoyl)-docetaxel for the Treatment of Breast Cancer
A docetaxel (DX) lipid conjugate 2’-(2-bromohexadecanoyl)-docetaxel (2-Br-C16-DX) is synthesized to enhance the drug loading, entrapment and retention in liquid oil-filled lipid nanoparticles (NPs). The conjugate is successfully entrapped in the previously optimized NPs with an entrapment efficiency...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3858483/ https://ncbi.nlm.nih.gov/pubmed/23606545 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201300017 |
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