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CD47 signaling regulates the immunosuppressive activity of VEGF in T cells()

Thromobospondin-1 inhibits angiogenesis in part by interacting with the ubiquitous cell surface receptor CD47. In endothelial cells, CD47 interacts directly with vascular endothelial growth factor receptor-2 (VEGFR2), and thrombospondin-1 inhibits VEGFR2 phosphorylation and signaling by disrupting t...

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Detalhes bibliográficos
Main Authors: Kaur, Sukhbir, Chang, Tiffany, Singh, Satya P., Lim, Langston, Mannan, Poonam, Garfield, Susan H., Pendrak, Michael L., Pantoja, David R. Soto, Rosenberg, Avi Z., Jin, Shelly, Roberts, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4185246/
https://ncbi.nlm.nih.gov/pubmed/25200950
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1303116
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