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PDGF-D Expression Is Down-Regulated by TGFβ in Fibroblasts
Transforming growth factor-β (TGFβ) is a key mediator of fibrogenesis. TGFβ is overexpressed and activated in fibrotic diseases, regulates fibroblast differentiation into myofibroblasts and induces extracellular matrix deposition. Platelet-derived growth factor (PDGF) is also a regulator of fibrogen...
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| Главные авторы: | , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4184810/ https://ncbi.nlm.nih.gov/pubmed/25280005 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108656 |
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