PDGF-D Expression Is Down-Regulated by TGFβ in Fibroblasts

Transforming growth factor-β (TGFβ) is a key mediator of fibrogenesis. TGFβ is overexpressed and activated in fibrotic diseases, regulates fibroblast differentiation into myofibroblasts and induces extracellular matrix deposition. Platelet-derived growth factor (PDGF) is also a regulator of fibrogen...

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Hlavní autoři: Charni Chaabane, Saima, Coomans de Brachène, Alexandra, Essaghir, Ahmed, Velghe, Amélie, Lo Re, Sandra, Stockis, Julie, Lucas, Sophie, Khachigian, Levon M., Huaux, François, Demoulin, Jean-Baptiste
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4184810/
https://ncbi.nlm.nih.gov/pubmed/25280005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0108656
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