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Idiopathic basal ganglia calcification-associated PDGFRB mutations impair the receptor signalling
Platelet-derived growth factors (PDGF) bind to two related receptor tyrosine kinases, which are encoded by the PDGFRA and PDGFRB genes. Recently, heterozygous PDGFRB mutations have been described in patients diagnosed with idiopathic basal ganglia calcification (IBGC or Fahr disease), a rare inherit...
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| Udgivet i: | J Cell Mol Med |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4288366/ https://ncbi.nlm.nih.gov/pubmed/25292412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.12443 |
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