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Direct Reaction of Amides with Nitric Oxide To Form Diazeniumdiolates
[Image: see text] We report the apparently unprecedented direct reaction of nitric oxide (NO) with amides to generate ions of structure R(C=O)NH–N(O)=NO(–), with examples including R = Me (1a) or 3-pyridyl (1b). The sodium salts of both released NO in pH 7.4 buffer, with 37 °C half-lives of 1–3 min....
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| 主要な著者: | , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Chemical
Society
2014
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| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4184460/ https://ncbi.nlm.nih.gov/pubmed/25210948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo501670e |
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