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Cell-Permeable Esters of Diazeniumdiolate-Based Nitric Oxide Prodrugs

[Image: see text] Although O(2)-(2,4-dinitrophenyl) derivatives of diazeniumdiolate-based nitric oxide (NO) prodrugs bearing a free carboxylic acid group were activated by glutathione to release NO, these compounds were poor sources of intracellular NO and showed diminished anti-proliferative activi...

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Bibliographische Detailangaben
Veröffentlicht in:Org Lett
Hauptverfasser: Chakrapani, Harinath, Maciag, Anna E., Citro, Michael L., Keefer, Larry K., Saavedra, Joseph E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6939382/
https://ncbi.nlm.nih.gov/pubmed/18956868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol8020989
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