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Total Synthesis of (+)-18-epi-Latrunculol A: Development of a Synthetic Route
[Image: see text] The evolution of an enantioselective total synthesis of (+)-18-epi-latrunculol A, a congener of the marine-sponge-derived latrunculins A and B, is reported. Key steps include a late-stage Mitsunobu macrolactonization to construct the 16-membered macrolactone, a mild Carreira alkyny...
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| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Chemical
Society
2014
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4184459/ https://ncbi.nlm.nih.gov/pubmed/25243951 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jo501733m |
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