Genetic variant in folate homeostasis is associated with lower warfarin dose in African Americans

The anticoagulant warfarin has >30 million prescriptions per year in the United States. Doses can vary 20-fold between patients, and incorrect dosing can result in serious adverse events. Variation in warfarin pharmacokinetic and pharmacodynamic genes, such as CYP2C9 and VKORC1, do not fully expl...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Daneshjou, Roxana, Gamazon, Eric R., Burkley, Ben, Cavallari, Larisa H., Johnson, Julie A., Klein, Teri E., Limdi, Nita, Hillenmeyer, Sara, Percha, Bethany, Karczewski, Konrad J., Langaee, Taimour, Patel, Shitalben R., Bustamante, Carlos D., Altman, Russ B., Perera, Minoli A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Hematology 2014
Soggetti:
Thrombosis and Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183989/
https://ncbi.nlm.nih.gov/pubmed/25079360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2014-04-568436
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi