Pathway analysis of genome-wide data improves warfarin dose prediction

BACKGROUND: Many genome-wide association studies focus on associating single loci with target phenotypes. However, in the setting of rare variation, accumulating sufficient samples to assess these associations can be difficult. Moreover, multiple variations in a gene or a set of genes within a pathw...

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Hlavní autoři: Daneshjou, Roxana, Tatonetti, Nicholas P, Karczewski, Konrad J, Sagreiya, Hersh, Bourgeois, Stephane, Drozda, Katarzyna, Burmester, James K, Tsunoda, Tatsuhiko, Nakamura, Yusuke, Kubo, Michiaki, Tector, Matthew, Limdi, Nita A, Cavallari, Larisa H, Perera, Minoli, Johnson, Julie A, Klein, Teri E, Altman, Russ B
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2013
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829086/
https://ncbi.nlm.nih.gov/pubmed/23819817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-14-S3-S11
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