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VKORC1 Asp36Tyr geographic distribution and its impact on warfarin dose requirements in Egyptians

The VKORC1 Asp36Tyr single nucleotide polymorphism (SNP) is one of the most promising predictors of high warfarin dose, but data on its population prevalence is incomplete. We determined the frequency of this SNP in participants from seven countries on four continents and investigated its effect on...

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Bibliographic Details
Main Authors: Shahin, Mohamed Hossam A., Cavallari, Larisa H., Perera, Minoli A., Khalifa, Sherief I., Misher, Anne, Langaee, Taimour, Patel, Shitalben, Perry, Kimberly, Meltzer, David O., McLeod, Howard L., Johnson, Julie A.
Format: Artigo
Language:Inglês
Published: 2013
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712827/
https://ncbi.nlm.nih.gov/pubmed/23571513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH12-10-0789
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