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VKORC1 Asp36Tyr geographic distribution and its impact on warfarin dose requirements in Egyptians

The VKORC1 Asp36Tyr single nucleotide polymorphism (SNP) is one of the most promising predictors of high warfarin dose, but data on its population prevalence is incomplete. We determined the frequency of this SNP in participants from seven countries on four continents and investigated its effect on...

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Autors principals: Shahin, Mohamed Hossam A., Cavallari, Larisa H., Perera, Minoli A., Khalifa, Sherief I., Misher, Anne, Langaee, Taimour, Patel, Shitalben, Perry, Kimberly, Meltzer, David O., McLeod, Howard L., Johnson, Julie A.
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712827/
https://ncbi.nlm.nih.gov/pubmed/23571513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH12-10-0789
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