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VKORC1 Asp36Tyr geographic distribution and its impact on warfarin dose requirements in Egyptians

The VKORC1 Asp36Tyr single nucleotide polymorphism (SNP) is one of the most promising predictors of high warfarin dose, but data on its population prevalence is incomplete. We determined the frequency of this SNP in participants from seven countries on four continents and investigated its effect on...

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Detalhes bibliográficos
Main Authors: Shahin, Mohamed Hossam A., Cavallari, Larisa H., Perera, Minoli A., Khalifa, Sherief I., Misher, Anne, Langaee, Taimour, Patel, Shitalben, Perry, Kimberly, Meltzer, David O., McLeod, Howard L., Johnson, Julie A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712827/
https://ncbi.nlm.nih.gov/pubmed/23571513
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1160/TH12-10-0789
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