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Impact of GGCX, STX1B and FPGS Polymorphisms on Warfarin Dose Requirements in European‐Americans and Egyptians

Genotype‐based algorithms that include VKORC1 and CYP2C9 genotypes are less predictive of warfarin dose variability in Africans as opposed to Europeans. Polymorphisms in GGCX, FPGS, or STX1B are associated with warfarin dose requirements in African‐Americans. We sought to determine if they influence...

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Detalhes bibliográficos
Publicado no:Clin Transl Sci
Main Authors: Hamadeh, IS, Shahin, MH, Lima, SM, Oliveira, F, Wilson, L, Khalifa, SI, Langaee, TY, Cooper‐DeHoff, RM, Cavallari, LH, Johnson, JA
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4760888/
https://ncbi.nlm.nih.gov/pubmed/26751406
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12385
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