The Cellular Redox Environment Alters Antigen Presentation

Cysteine-containing peptides represent an important class of T cell epitopes, yet their prevalence remains underestimated. We have established and interrogated a database of around 70,000 naturally processed MHC-bound peptides and demonstrate that cysteine-containing peptides are presented on the su...

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Главные авторы: Trujillo, Jonathan A., Croft, Nathan P., Dudek, Nadine L., Channappanavar, Rudragouda, Theodossis, Alex, Webb, Andrew I., Dunstone, Michelle A., Illing, Patricia T., Butler, Noah S., Fett, Craig, Tscharke, David C., Rossjohn, Jamie, Perlman, Stanley, Purcell, Anthony W.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183829/
https://ncbi.nlm.nih.gov/pubmed/25135637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.573402
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