Virus-Specific Memory CD8 T Cells Provide Substantial Protection from Lethal Severe Acute Respiratory Syndrome Coronavirus Infection

Severe acute respiratory syndrome coronavirus (SARS-CoV) caused an acute human respiratory illness with high morbidity and mortality in 2002-2003. Several studies have demonstrated the role of neutralizing antibodies induced by the spike (S) glycoprotein in protecting susceptible hosts from lethal i...

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Bibliographic Details
Main Authors: Channappanavar, Rudragouda, Fett, Craig, Zhao, Jincun, Meyerholz, David K., Perlman, Stanley
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2014
Subjects:
Pathogenesis and Immunity
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178831/
https://ncbi.nlm.nih.gov/pubmed/25056892
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01505-14
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