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Reduced Plasminogen Binding and Delayed Activation Render γ′-Fibrin More Resistant to Lysis than γ(A)-Fibrin

Fibrin (Fn) clots formed from γ′-fibrinogen (γ′-Fg), a variant with an elongated γ-chain, are resistant to lysis when compared with clots formed from the predominant γ(A)-Fg, a finding previously attributed to differences in clot structure due to delayed thrombin-mediated fibrinopeptide (FP) B relea...

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Detalhes bibliográficos
Main Authors: Kim, Paul Y., Vu, Trang T., Leslie, Beverly A., Stafford, Alan R., Fredenburgh, James C., Weitz, Jeffrey I.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4183790/
https://ncbi.nlm.nih.gov/pubmed/25128532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.588640
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