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Batroxobin Binds Fibrin with Higher Affinity and Promotes Clot Expansion to a Greater Extent than Thrombin

Batroxobin is a thrombin-like serine protease from the venom of Bothrops atrox moojeni that clots fibrinogen. In contrast to thrombin, which releases fibrinopeptide A and B from the NH(2)-terminal domains of the Aα- and Bβ-chains of fibrinogen, respectively, batroxobin only releases fibrinopeptide A...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Vu, Trang T., Stafford, Alan R., Leslie, Beverly A., Kim, Paul Y., Fredenburgh, James C., Weitz, Jeffrey I.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3675619/
https://ncbi.nlm.nih.gov/pubmed/23612970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.464750
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