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A CD40-targeted peptide controls and reverses type 1 diabetes in NOD mice
AIMS/HYPOTHESIS: The CD40–CD154 interaction directs autoimmune inflammation. Therefore, a longstanding goal in the treatment of autoimmune disease has been to control the formation of that interaction and thereby prevent destructive inflammation. Antibodies blocking CD154 are successful in mouse mod...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2014
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4183717/ https://ncbi.nlm.nih.gov/pubmed/25104468 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-014-3342-5 |
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