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A CD40 targeting peptide prevents severe symptoms in Experimental Autoimmune Encephalomyelitis
CD40/CD154-interaction is critical in the development of Experimental Autoimmune Encephalomyelitis (EAE; mouse model of Multiple Sclerosis). Culprit CD4(+)CD40(+) T cells drive a more severe form of EAE than conventional CD4 T cells. Blocking CD40/CD154-interaction with CD154-antibody prevents or am...
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| Udgivet i: | J Neuroimmunol |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6535109/ https://ncbi.nlm.nih.gov/pubmed/30925295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2019.03.013 |
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