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An alternative role for FoxP3 as an effector T cell regulator controlled through CD40

The BDC2.5 T cell clone is highly diabetogenic, but the transgenic mouse generated from that clone is surprisingly slow in diabetes development. While defining pathogenic effector T cells in autoimmunity has been inconsistent, CD4(+) cells expressing the CD40 receptor (Th40 cells) are highly diabeto...

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Detalhes bibliográficos
Main Authors: Vaitaitis, Gisela M., Carter, Jessica R., Waid, Dan M., Olmstead, Michael, Wagner, David H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3712636/
https://ncbi.nlm.nih.gov/pubmed/23776180
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1300625
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